This sequence taken with the polarizing microscope in 1967 shows the reversible enhancement of spindle volume and birefringence by heavy water in arrested metaphase oocyte of Pectinaria gouldi (ice cr...

Dividing eggs of the medusa Clypeaster japonicus showing birefringent spindles and fertilization envelopes. The arrow indicates the direction of the compensator slow axis. As the direction of compensa...

Mouse myoblasts stably transfected with GFP-PCNA to label replication foci and the 3D distribution of the GFP signal recorded over time using a confocal microscope. The time series illustrates the dyn...

Confocal"Brainbow" mouse hippocampus and cerebral cortex neurons, with several fields montaged together. In Brainbow mice, neurons randomly choose combinations of red, yellow and cyan fluorescent pro...

Distribution of Nup133, Nup43 and Nup62 (green) and tubulin (blue) in spindles assembled in vitro from Xenopus oocyte extracts. Chromosomes are stained with DAPI (blue). See Orjalo et al 2006. Mol Bio...

Shown is a fibroblast from a Hutchinson-Gilford Progeria syndrome patient which carries a mutation in the gene for lamin A (left image, red), a major component of the nuclear lamina. Also shown is th...

Mouse myoblast cells were engineered to express GFP-PCNA (proliferating cell nuclear antigen) as a marker for replication factories, and also immunostained for DNA ligase. DNA was localized using Hoec...

Cells of the symbiotic prochlorophyte Prochloron didemni were separated from its ascidian partner, thylakoids isolated, treated to liberate chlorophyll-containing complexes, and negatively stained pre...

EM images of chromatin fibers reconstituted from tandem arrays of a strong nucleosome positioning sequence flanked by different lengths of 'linker' DNA, to create nucleosome repeat lengths (NRL) from ...

Images of negatively stained chromatin fibers prepared from tandem arrays of a nucleosome positioning sequence reconstituted with purified histones. These samples contained 80 repeats of a 167 bp DNA ...