Transmission electron micrograph of a vacuole from a sertraline-treated chc1 mutant cell. This vacuole shows evidence of active autophagy. This image is a high-magnification zoom of the cell in CIL 40...

Transmission electron micrograph of a mature autophagosome from a BY4716 wildtype cell treated with 60µM sertraline. (40,000X). CIL 40414 is a similarly treated cell.

Developing trichocyst containing a paracrystalline core surrounded by amorphous material and an autophagosome containing mitochodrion. TEM taken on 1/25/74 by R. Allen with Hitachi HU11A operating at ...

Saccharomyces cerevisiae (WT BY4741-MATa his3Δ1 leu2Δ0 met15Δ0 ura3Δ0) undergoing chronological aging on small synthetic 2% glucose media (SMD) with supplementation of 4 mM spermidine. Spermidine ...

Human colon carcinoma HCT 116 cells were transfected with a GFP-LC3-encoding plasmid, cultured in complete medium for 24 h and treated with µM Resveratrol for 4 h. For fluorescence microscopy determi...

Human colon carcinoma HCT 116 cells were transfected with a GFP-LC3-encoding plasmid, cultured in complete medium for 24 h and treated with 100 µM Resveratrol in the presence of the SIRT1 inhibitor E...

Developing trichocyst containing a paracrystalline core surrounded by amorphous material and an autophagosome containing mitochodrion. TEM taken on 1/25/74 by R. Allen with Hitachi HU11A operating at ...

Human colon carcinoma HCT 116 cells were transfected with an siRNA specific for SIRT1 and then retransfected with a GFP-LC3-encoding plasmid, cultured in complete medium for 24 h and left untreated fo...

Human colon carcinoma HCT 116 cells were transfected with a GFP-LC3-encoding plasmid, cultured in complete medium for 24 h and enucleated to obtain cytoplasts. The cytoplasts were treated with 100 µM...

Human colon carcinoma HCT 116 cells were transfected with a GFP-LC3-encoding plasmid, cultured in complete medium for 24 h and enucleated to obtain cytoplasts. The cytoplasts were treated with 100 µM...